Prediction of sudden death in hypertrophic cardiomyopathy

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Prevention of Sudden Death in Hypertrophic Cardiomyopathy

C ase presentation: A 14-yearold girl died suddenly and unexpectedly while exercising. Clinical and echocardiographic family screening identified hypertrophic cardiomyopathy (HCM) in her only sibling, an asymptomatic 17-year-old boy. In her brother, echocardiography showed extreme septal ventricular hypertrophy, 35 mm in thickness; left ventricular (LV) outflow obstruction was absent. Left atri...

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Sudden cardiac death risk in hypertrophic cardiomyopathy.

It is well recognized that sudden cardiac death (SCD) is an infrequent, unpredictable, but catastrophic complication of hypertrophic cardiomyopathy (HCM). In population-based studies the overall SCD rate is 1% per year among patients with a clinical diagnosis of HCM. A crucial aspect of the management of patients with HCM is an assessment of each individual patient’s risk for SCD so that preven...

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Sudden cardiac death in hypertrophic cardiomyopathy.

Introduction Hypertrophic cardiomyopathy (HCM) is a common disorder of cardiac muscle associated with sudden cardiac death (SCD). HCM is defined by increased left ventricular wall thickness or mass, in the absence of abnormal loading conditions to account for the observed abnormality. In most adults, the disease is inherited as an autosomal dominant trait and is caused by mutations in cardiac s...

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Apical Hypertrophic Cardiomyopathy in a Case with Chest Pain and Family History of Sudden Cardiac Death: A Case Report

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease, which is caused by a multitude of mutations in genes encoding proteins of the cardiac sarcomere (1). Apical hypertrophic cardiomyopathy (AHCM) is an uncommon type of HCM. The sudden cardiac death is less likely to occur in the patients inflicted with AHCM (2). Herein, we presented the case of a 29-year-old man ...

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Hypertrophic Cardiomyopathy Sudden Death in Hypertrophic Cardiomyopathy: Identification of High Risk Patients

OBJECTIVES We sought to identify patients with hypertrophic cardiomyopathy (HCM) at high risk of sudden death (SD). BACKGROUND Relatively low mortality rates in HCM make conventional analysis of multiple clinical risk markers for SD problematic. This study used a referral center registry to investigate a smaller number of generally accepted noninvasive risk markers. METHODS We studied 368 patie...

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ژورنال

عنوان ژورنال: Heart

سال: 1992

ISSN: 1355-6037

DOI: 10.1136/hrt.68.7.37